Stat to know: Jacksonville receiver DJ Chark Jr. has 19 receptions for 321 yards and three scores this season. ET | Fox Paired with fellow receivers John Brown and Jaron Brown, the Arizona wideouts pose a threat to a vulnerable Eagles cornerback group. Raiders 23, Ravens 16 -- Paul Gutierrez, Three key players from the Packers playoff victory over the Cowboys are gone -- Jared Cook (the tight end who caught the sideline pass to set up the game-winning field goal), Micah Hyde (the safety who had an interception) and T.J. Lang (the Pro Bowl guard who protected Aaron Rodgers). No one really knows what to expect. Jets 24, Browns 10 -- Pat McManamon, The Lions are strong against the run, which makes the timing of Panthers quarterback Cam Newton finding his timing against New England most important. Click on each game for the game preview and CFN Prediction Week 5 NFL Expert Picks NFL best bets and picks for Week 5: Take the 49ers and the points, and the Jets-Falcons over. Colts vs Broncos starts the week off on Thursday Night Football. But the Commanders' run defense will be severely tested by Tennessee running back Derrick Henry. Matchup rating: 49.4 | Spread: LAC -6.5 (44.5), What to watch for: With Denver desperate for a win and fellow edge rusher Bradley Chubb done for the year because of an ACL injury, look for Von Miller to ignite the Broncos by getting after Philip Rivers, who has limited mobility. Read more. Davenport's pick: Titans 17, Bills 14 These two teams played last year in similar circumstances, with the Titans leaving with the victory due to Mariota's four touchdowns and a stout running game. NFL Week 5 Early Odds, Picks & Predictions (2022) by Jason Radowitz | Sep, 29 2022 Before Week 4 begins, there's plenty of value with some Week 5 lines. What to know for fantasy: Dalvin Cook has rushed for a touchdown in all four weeks this season and has seen his reception total increase each week as he continues to make a bid as a top-tier fantasy RB. But this week, players and coaches have been quick to say that was one game and the Chiefs present a different challenge. Cincinnati Bengals vs. Baltimore Ravens picks, predictions NFL Week 5 Moody's pick: 49ers 27, Panthers 10 The Chiefs' offense is a complete running and passing groove with Patrick Mahomes. -- Jake Trotter. Wagoner's pick: 49ers 27, Browns 24 Matchup rating: 40.4 | Spread: CAR -3.5 (41), What to watch for: Both teams will be relying on top running backs from the 2017 draft to take the pressure off young quarterbacks. While they are struggling in the passing game, the Bears are third in the NFL in rushing yards (709). These two teams just played each other in the regular season finale last week when the Roughnecks won 25-9 despite Brandon Silvers, Max Borghi, Deontay Burnett, and Brycen Alleyne all sitting. After catching eight passes for 111 yards in the season opener, he has not reached 70 receiving yards in any of the past three games. Cimini's pick: Eagles 27, Jets 9 His six catches last week against the Chargers are 60% of his grabs for the season. NFL Expert Picks - Super Bowl Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Week 15 Week 16 Week 17 Week 18 Wild Card Divisional Round Conference Championship Super Bowl hidden The 61-0 streak is over: Why the Ravens are no longer the NFL's best closers, Monday 8:15 p.m. NFL Week 5 picks, schedule, odds, injuries, stats, fantasy tips Betting nugget: All four Bills games have gone under the total this season. McClure's pick: Texans 24, Falcons 21 Even at full strength, Seattle's offensive line will have its hands full against a Rams front four that has given the Seahawks all sorts of trouble during the past few seasons. FPI prediction: CAR, 56.2% (by an average of 1.8 points), Matchup must-reads: Jimmie Ward year away from being among rarefied 49ers company Mayfield struggles, but Panthers don't have another option Nick Bosa says 49ers' defense has personnel to be 'best in the league' Mayfield takes blame for offense's struggles amid 1-3 start Darnold's return from IR not close, coach Matt Rhule says, 4:25 p.m. Our NFL Nation reporters bring us the biggest keys to every game and a bold prediction for each matchup. CFB: The way-too-early top 25 for 2021 -- Courtney Cronin. That was a reminder that their defense remains one of the NFL's best. Yes, he's 2-0, but the Saints will need more from Bridgewater, 1 p.m. ESPN Reporter Claims Aaron Rodgers Deal Affected NFL Schedule Release The Bolts are averaging an NFL-low 64.5 rushing yards per game, while the Browns' defense is ranked 17th, allowing an average of 113 yards per game. play. The team has preached all week that their offense won't change much with the backup quarterback starting, and he'll prove them right come Sunday. (1:17). Stat to know: Jared Goff is tied for the lead in passing touchdowns with 11. It sounds crazy, but the Jets will win their third straight game. Arizona has given up 17 sacks while the Eagles have 10 on the season, but Palmer called the Eagles' front seven one of the best he will face this year. Betting nugget: Atlanta has failed to cover 13 straight games against AFC opponents (1-12 outright). -- Vaughn McClure. To take advantage of the Ravens' weak spot, the Steelers could push Rudolph to unleash more deep throws. Spread: GB -8.0 (41), What to watch for: This could be a nightmare matchup for the Packers' defense. Rodgers hasn't topped 255 yards passing this season, and the Giants have the eighth-ranked pass defense. ET games. The latest hint that the Jets are destined for the spotlight came from ESPN's Adam Schefter. Another one of its Week 5 NFL predictions: The Packers (-3) cover on the road against the Bengals in a matchup of 3-1 teams. Panthers QB Young all 'business now', Bold prediction: Bears rookie running back David Montgomery finally breaks through with 100 rushing yards. Thursday night is going to be fun. "His quickness with power is awesome," said Rivers about Miller, who has 16 career sacks against the Chargers. Betting nugget: Smith is 23-15 ATS in his career, including 10-2 ATS in his past 12 starts and 5-2 ATS with Seattle. What to know for fantasy: Baker Mayfield averaged one touchdown pass every 18 attempts as a rookie. -- Adam Teicher, Bold prediction: Raiders cornerback Amik Robertson will have a takeaway against the Chiefs. Levis opens up about draft day Facebook; Twitter; Facebook Messenger; Pinterest; Email; Scoring is up across the NFL. With Chris Carson gone, can Rashaad Penny 'take off' as Seattle Seahawks' RB1? But theyll defeat him as they have other young quarterbacks except for Oaklands Derek Carr as a rookie in 2014. 2023 NFL Draft live tracker: 4th through 7th round picks, analysis FPI prediction: NE, 85.7% (by an average of 14.7 points), Matchup must-reads: Meet Brady's most trusted teammate: His 1995 shoulder pads Redskins' January decision to maintain status quo looks bad in hindsight Patriots' offense searching for identity, as it did in 2018, 1 p.m. ET | ESPN/ESPN App Depth charts for every team Pick NFL winners straight up or against the spread and compete to win more than $14,400 in prizes! The Steelers have allowed three touchdowns on passes that have traveled at least 25 yards in the air, tied for third worst in the NFL. Steelers 27, Jaguars 20 -- Jeremy Fowler, The Seahawks are coming off one of the more dominant halves of football they've played under Pete Carroll, outscoring the Colts 36-3 and holding them to 32 yards in the second half last week. Matchup rating: 53.8 | Spread: TEN -3 (38.5), What to watch for: Marcus Mariota has not thrown an interception this season, but the Bills are tied with the Giants and 49ers for second in the NFL with five picks each. Week 5 brings some more great matchups and potential upsets. Spread: PHI -5.0 (49.5), What to watch for: The Cardinals will have their work cut out for them passing and defending the ball. That stat line would be worth 259.6 points, not much different from the 260.1 points that Allen produced last season. TB-NO | ATL-HOU | BUF-TEN NFL Expert Picks - Super Bowl Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Week 15 Week 16 Week 17 Week 18 Wild Card Divisional Round . "That's why he's one of the best [defensive] ends/outside 'backers ever." So it is possible things don't get better for Stafford this week. ET | CBS They'll be energized, while at home against a tough division rival, and will sneak out another close win. What to know for fantasy: Najee Harris averaged over 4.0 yards per carry for the first time this season last week, but he failed to record a reception in Pickett's NFL debut. Matchup rating: 56.9 | Spread: SF -3.5 (46.5), What to watch for: The 49ers are missing left tackle Joe Staley and cornerback Ahkello Witherspoon, both of whom play positions opposite Cleveland's best players in defensive end Myles Garrett (and DE/LB Olivier Vernon, depending on alignment) and receiver Odell Beckham Jr. With backups in the lineup, can the Niners neutralize two of Cleveland's biggest stars? Stat to know: The Niners' Jeff Wilson Jr. has scored multiple rushing touchdowns in two straight games. FPI prediction: KC, 80.9% (by an average of 12.0 points), Matchup must-reads: Mahomes, Favre and other NFL stars reveal the larger-than-life tales behind Andy Reid Colts GM Chris Ballard has needed his no-flinch, no-panic approach Chiefs RB Williams has waited behind big-name backs before Ebron 'disgusted' by drops, takes blame for Colts' loss, Monday, 8:15 p.m. Jalen Ramsey to the Eagles: What are the realistic odds? It prompted Packers coach Matt LaFleur to say this week that defensive coordinator Joe Barry needs to have his players "play more physical" and "in certain situations you might have to put an extra defender in the box." Betting nugget: Brandon Staley is 1-3 outright and ATS as a road favorite (won last week). And regardless of whos at quarterback, Adam Thielen and Stefon Diggs need to spark the Vikings' aerial attack early while the running game gets in its groove with Latavius Murray taking the reins for an injured Dalvin Cook. FPI prediction: LAC, 65.1% (by an average of 5.4 points), Matchup must-reads: Broncos' 'world of suck' won't be easily fixed How Chargers kept team from splintering during Gordon holdout Chubb's injury further exposes Broncos' house of cards, 4:25 p.m. What to know for fantasy: Derek Carr has completed over 70% of his passes in four straight games against the Chiefs and cleared 18 fantasy points in three of those contests. What to know for fantasy: After scoring 11 times in his first 14 games last season, Hopkins has scored just twice in his past seven games (playoffs included). FPI prediction: NO, 72.6% (by an average of 6.9 points), Matchup must-reads: The Seahawks have needed every bit of Geno Smith's unlikely success Andy Dalton gave Saints' offense a spark, but bigger issues loom after 1-3 start Saints' Alvin Kamara (rib) expects to play against Seahawks, What to watch for: Washington has done a nice job stopping the run the past two weeks against the Eagles and Cowboys, allowing an NFL-best 2.27 yards per carry and tying for second at 67 yards allowed during that stretch. See Week 5 rankings. -- Eric D. Williams, Bold prediction: The Broncos have not intercepted a pass this season, but they will get their first one Sunday. The story of the Cowboys scout and prospect son Dallas just drafted, Legacy pick: Cardinals take great-great-nephew of team's first-ever draft pick, Winston already improving under 'QB whisperer' Bruce Arians, Yes, he's 2-0, but the Saints will need more from Bridgewater, Matthew Berry's Love/Hate for Week 5: How to make a trade, NFL experts predict: Week 5 upset picks, fantasy football flops and sleepers, How Watson's 'NFL experience' began as ball boy for the Falcons, TE Hooper could be the next Falcon to cash in, Taylor Lewan's return could be a boon for Titans' offense, Gore closing on No. Read more. -- Marcel Louis-Jacques. What to know for fantasy: Since Week 15 of the 2017 season, just once has a player rushed for 90 yards against the Steelers in Pittsburgh. The Jaguars were leading the NFL in rush defense until giving up 210 yards and four rushing touchdowns in a loss at Philadelphia last weekend. Peyton Manning is getting his own statue in front of the stadium and will have his jersey retired Sunday. The last thing the Vikings need is for Diggs' situation to blow up into a full-blown distraction. The Colts, like in previous seasons, are struggling statistically on defense, ranking 31st overall. -- Katherine Terrell, Bold prediction: Ryan Neal will take over for Josh Jones in the starting lineup and spark Seattle's struggling defense with a game-changing takeaway. ET | Fox Betting nugget: Bridgewater is 25-7 against the spread (ATS) in his career as a starting quarterback, the best mark by any QB with at least 15 starts in the Super Bowl era. More: NFL Week 5 odds: Money lines, point spreads, over/under for every Week 5 NFL game. -- Josh Weinfuss, Bold prediction: Arizona will double its sack total on the season and take Jalen Hurts down four times. Without Tyreek Hill, Chiefs' receiving load shifting to tight ends and backs Patrick Mahomes says Andy Reid 'stole the show' in TV ad, 9:30 a.m. Big Ben's 3-1 home-away touchdown ratio since 2015 looms large here, especially with Bell looking like his 2016 self and Jacksonville entering the week allowing 5.7 yards per carry, the league's worst by a large margin. ET | CBS The Saints, meanwhile, have committed an NFL-high 11 turnovers -- including five interceptions in three games from Jameis Winston -- so the opportunity will be there. New England's slide has coincided with losing DT Lawrence Guy (shoulder), who might be ready to return. Read more. Theyll give up some yards and some plays. See Week 5 rankings. While he acquitted himself generally well in a tough spot when Mailata went down against the Jaguars on Sunday, Arizona should have some opportunities to affect the passer. See Week 5 rankings. Allgeier and Caleb Huntley will handle the majority of the work with Patterson (knee) on injured reserve, and the two young backs will alternate to cause problems for the Buccaneers. This week's draft seemingly begins with the second overall pick -- excluding Tuesday's wild odds move for the top pick -- but it could take a few wild turns right after that. The Cardinals have allowed a league-high 20 sacks; the Bengals are right behind them at 19. The Chiefs are averaging 5.2 yards per rush this season with McCoy on the field, compared to 3.3 with him off the field. So this is a game the Chargers normally would lose, which is why Im picking them to win -- along with the fact that I believe the Giants will have trouble stopping the Bolts talented pass-rushing duo of Melvin Ingram and Joey Bosa. It ranks in the bottom third of the NFL in yards allowed per carry (5.0), and the Giants -- with the NFL's leading rusher, Saquon Barkley -- run it at the second-best clip in the league (5.8 yards per carry). NFL Week 5 odds: Colts vs. Broncos | Giants vs. Packers | Steelers vs. Bills Chargers vs. Browns | Texans vs. Jaguars | Bears vs. Vikings Lions vs. Patriots | Seahawks vs. Saints | Dolphins. NFL schedule 2021: Week 5 picks, odds, predictions, best - SportsLine The 2023 NFL draft wrapped up Saturday and through five rounds, 12 quarterbacks were selected -- the most in the common draft era. So, these teams could have to rely on their defenses. Given the Colts' struggles protecting the quarterback (they've allowed 14 sacks, tied for fifth most in the league) and the Niners' ability to take advantage of porous offensive lines (nine sacks total against Seattle and Arizona), this would seem to be the type of game the 49ers can win. Betting nugget: Atlanta is 4-0 ATS this season, all as an underdog. Betting nugget: Arizona is 19-9 ATS in September/October under Kliff Kingsbury (12-3 ATS in October). Moody's pick: Packers 31, Giants 14 Prediction: Cowboys 28, Giants 17. They won't do anything to change that with a big win over the Giants. But in Cooks' five career games against the Jaguars, he has averaged 120 yards with five touchdowns.

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